|
Cox proportional hazards
- time-varying covariates and censoring
- continuously time-varying covariates allowed
- conventional or robust estimates of variance
- stratified estimation
- sampling weights
- four ways to handle ties: Breslow, exact partial likelihood, exact marginal likelihood, and Efron
- martingale, efficient score, Cox–Snell, Schoenfeld, and deviance residuals
- tests for proportional hazards
- estimates of baseline survival, hazard, and cumulative hazard functions
- shared frailty models
- Harrell's C and Somers' D statistics measuring concordance*
Parametric survival models
- exponential
- Weibull
- Gompertz
- lognormal
- log-logistic
- generalized log-gamma
- martingale-like, score, Cox–Snell, Schoenfeld, and deviance residuals
- plots of predicted survival, hazard, and cumulative hazard functions
- individual-level frailty
- group-level or shared frailty
- stratified models
- linear constraints
Features of survival models
- single or multiple failure data
- left truncation
- right censoring
- time-varying regressors
- gaps
- recurring events
- start-stop format
- different types of failure events
- multiple time scales allowed
- conventional or robust estimates of variance
|
|
Kaplan–Meier and Nelson–Aalen
- graph estimates and confidence intervals
- list estimates and confidence intervals
- test (log-rank, Mantel–Haenszel, Wilcoxon–Breslow, Tarone–Ware, Fleming–Harrington, Peto–Peto–Prentice)
- test for trend
- calculate level and confidence interval of survivor function
- report mean survival time and confidence interval
- Cox regression-adjusted estimates (optional)
Summary tables
- time at risk, incidence rate, number of subjects, 25th, 50th, and 75th percentiles of survival time
- incidence rate ratio and difference
- life tables
- rates and SMRs by one or more categorical variables
- stratified rate ratios
Utilities
- create nested case-control datasets
- split and join time records
- conver snapshot data into time-span data
- calculate person-time (person-years), incidence rates, and standardized mortality/morbidity ratios (SMR)
Predictions
- mean or median time to failure
- mean or median log time
- hazard
- hazard ratios
- survival probabilities
Marginal effects
- marginal effects and elasticities
- standard errors and confidence intervals
- at means or specified covariate values
- any predicted statistic
|